GTSCOPE - To Evaluate the Natural Progression of Dry Age-related Macular Degeneration (AMD)

A Study of Disease Progression in Genetically Defined Subjects With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)

ClinicalTrials.gov Identifier: NCT03894020

Novartis Reference Number: GTSCOPE

Last Update: Feb 24, 2021

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All compounds are either investigational or being studied for (a) new use(s). Efficacy and safety have not been established. There is no guarantee that they will become commercially available for the use(s) under investigation. 

Study Description

An observational study to evaluate the natural progression of dry AMD in genetically defined subjects

Condition 
Dry Age-related Macular Degeneration
Macular Degeneration
Retinal Disease
Retinal Degeneration
Geographic Atrophy
Macular Atrophy
Phase 
Not Given
Overall status 
Recruiting
Start date 
Jan 08, 2019
Completion date 
Jan 08, 2023
Gender 
All
Age(s)
18 Years and older (Adult, Older Adult)

Eligibility Criteria

Inclusion Criteria:

Adults with unilateral or bilateral Geographic Atrophy (GA) due to Age-related Macular Degeneration (AMD)
BCVA of 40 letters or better using ETDRS charts

Exclusion Criteria:

Evidence or history of neovascular Age-related Macular Degeneration (AMD) or diabetic retinopathy
Significant ocular or non-ocular disease that would impact the subject's ability to participate in the study
Participation in another research study involving an investigational product within the previous 4 weeks or 5 half-lives whichever is longer from the screening/baseline OR received a gene/cell therapy at any time previously

Study Locations

United States
Retina Vitreous Associates Medical Group
Recruiting
Beverly Hills, 90211
California
United States
Southeast Retina Center
Recruiting
Augusta, 30909
Georgia
United States
Georgia Retina PC
Recruiting
Marietta, 30060
Georgia
United States
University Retina Macula Associates PC
Recruiting
Lemont, 60452
Illinois
United States
Midwest Eye Institute Northside
Recruiting
Indianapolis, 46290
Indiana
United States
Wolfe Eye Clinic
Recruiting
West Des Moines, 50266
Iowa
United States
Johns Hopkins University School of Medicine
Recruiting
Baltimore, 21287
Maryland
United States
Ophthalamic Consultants of Boston (OCB)
Recruiting
Boston, 02114 - Massachusetts
Contact: Boston
United States
Pepose Vision Institute
Recruiting
Chesterfield, 63017
Missouri
United States
Sierra Eye Associates
Recruiting
Reno, 89502
Nevada
United States
New Jersey Retina Research Foundation
Recruiting
Vauxhall, 07088
New Jersey
United States
Long Island Vitreoretinal Consultants
Recruiting
Great Neck, 11021
New York
United States
Retina Association of Western New York
Recruiting
Rochester, 14620
New York
United States
Cincinnati Eye Institute
Recruiting
Cincinnati, 45227
Ohio
United States
Casey Eye Institute - OHSU
Recruiting
Portland, 97239
Oregon
United States
Mid-Atlantic Retina
Recruiting
Huntingdon Valley, 19107
Pennsylvania
United States
Mid-Atlantic Retina
Recruiting
Philadelphia, 19107
Pennsylvania
United States
The Retina Care Center
Recruiting
Dallas, 21209
Texas
United States
Retina Foundation of the Southwest
Recruiting
Dallas, 75231
Texas
United States
Retina Consultants of Houston-TMC
Recruiting
Houston, 77030
Texas
United States
Strategic Clinical Research
Recruiting
Willow Park, 76008 - Texas
Contact: Texas
United States
Retina Associates of Utah
Recruiting
Salt Lake City, 84107
Utah
United States
Retina Center Northwest
Recruiting
Silverdale, 98383
Washington
United States
Spokane Eye Clinical Research
Recruiting
Spokane, 99204
Washington
United States
West Virginia University
Recruiting
Morgantown, 26506
West Virginia
United States
Australia
The University of Melbourne - The Centre for Eye Research Australia (CERA)
Recruiting
East Melbourne, 3002
-
Australia
Lions Eye Institute (LEI) - Nedlands
Recruiting
Nedlands, 6009
-
Australia
France
Centre Ophthalmologique
Recruiting
Bordeaux,
-
France
Centre Hospitalier Intercommunal
Recruiting
Créteil, 94010
-
France
CHU Dijon - Hôpital Mitterrand
Recruiting
Dijon, 2100
-
France
Hopital de la Croix Rousse - GH Nord
Recruiting
Lyon, 69004
-
France
Centre Paradis Monticelli
Recruiting
Marseille, 13008
-
France
Centre Hospitalier Universitaire de Nantes (CHU de Nantes) - Hotel-Dieu
Recruiting
Nantes, 44093
-
France
Hopital Lariboisiere
Recruiting
Paris, 75010
-
France
Centre Hospitalier
Recruiting
Poitiers,
-
France
Germany
Universitaetsklinikum Hamburg-Eppendorf
Recruiting
Hamburg, 20246
-
Germany
University Hospital Schleswig-Holstein - Campus Luebeck
Recruiting
Lübeck, 23538
-
Germany
EyeNet Baden-Wuerttemberg
Recruiting
Munich, 80339
-
Germany
St. Franziskus-Hospital
Recruiting
Münster, 48145
-
Germany
MVZ ADTC Siegburg GmbH
Recruiting
Siegburg,
-
Germany
Augenklinik Sulzbach
Recruiting
Sulzbach, 66280
-
Germany
University Hospital
Recruiting
Tübingen,
-
Germany
Netherlands
Radboud Universitair Medisch Centrum
Recruiting
Nijmegen, 6525
-
Netherlands
Poland
Klinika Okulistyczna Jasne Blonia Sp. z o.o.
Recruiting
Łódź, 91-134
Rojna
Poland
Specjalistyczny Osrodek Okulistyczny Oculomedica
Recruiting
Bydgoszcz, 85-316
-
Poland
Oftalmika - Prywatna Klinika Okulistyczna
Recruiting
Bydgoszcz, 85-631
-
Poland
Caminomed
Recruiting
Tarnowskie Góry, 42-600
-
Poland
Spain
Instituto de microcirugía ocular
Recruiting
Barcelona, 08035
-
Spain
Hospital General de Catalunya Sant Cugat del Valles
Recruiting
Barcelona, 08915
-
Spain
VISSUM Mirasierra
Recruiting
Madrid, 28035
-
Spain
Hospital Clinico San Carlos
Recruiting
Madrid, 28040
-
Spain
Clinica Universidad de Navarra
Recruiting
Pamplona, 31008
-
Spain
United Kingdom
Salisbury NHS Foundation Trust
Recruiting
Salisbury, SP2 8BJ
Wiltshire
United Kingdom
NHS Greater Glasgow and Clyde
Recruiting
Glasgow, G12 0YN
-
United Kingdom
Leeds Hospital
Recruiting
Leeds, LS9 7TF
Contact: Leeds
United Kingdom
London Vision Clinic
Recruiting
London, W1G 7LA
Contact: London
United Kingdom
Manchester Royal Eye Hospital
Recruiting
Manchester, M13 9WL
-
United Kingdom
John Radcliffe Hospital
Recruiting
Oxford, OX3 9DU
-
United Kingdom
Southampton General Hospital
Recruiting
Southampton, SO16 6YD
-
United Kingdom
Sunderland Eye Infirmary
Recruiting
Sunderland, SR2 9HP
-
United Kingdom

Contacts

Name: 
Gyroscope Therapeutics
Phone: 

Have a question?

Call 1-888-669-6682 or email [email protected]