Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location

Efficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis.

 		Relapsing Multiple Sclerosis Phase3 Australia
Canada 		NCT06846281

Pelacarsen Roll-over Extension Program

 		Atherosclerotic Cardiovascular Disease Phase3 United States NCT06875973

Long-term Follow up Local Registry Study of Kymriah in South Korea

 		B-Cell Acute Lymphoblastic Leukemia, Diffuse Large B-Cell Lymphoma, Follicular Lymphoma Korea, Republic of NCT06785818

Inclisiran Effectiveness in China: a Pragmatic Randomized Trial

 		Coronary Heart Disease Phase4 China NCT06941792

Open-label Extension Study of Zigakibart in Adults With IgA Nephropathy.

 		Kidney Diseases, Kidney Diseases, Chronic, Urological Diseases, Glomerulonephritis, Glomerular Disease, Glomerulonephritis, IGA, Glomerulopathy, Immunoglobulin Disease Phase3 United States NCT06858319

Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC

 		Prostate Cancer Phase3 Australia
China
Singapore 		NCT06855277

Study to Evaluate the Impact of Iptacopan on Top of SOC on Biopsy Changes in Kidneys of Adult Patients With IgAN

 		Glomerulonephritis, IGA, Immunoglobulin A Nephropathy Phase2 Malaysia
United States 		NCT06797518

A Study to Evaluate Efficacy of Remibrutinib Compared to Dupilumab at Early Timepoints in Adults With Chronic Spontaneous Urticaria Inadequately Controlled by Second Generation H1-antihistamines

 		Chronic Spontaneous Urticaria (CSU) Phase3 United States NCT06868212

A Study of JSB462 (Luxdegalutamide) Plus Lutetium (177Lu) Vipivotide Tetraxetan in Patients With Metastatic Castration Resistant Prostate Cancer (mCRPC)

 		Prostatic Cancer, Castration-Resistant Phase2 Israel
Singapore
United States 		NCT07047118

A Study to Assess Safety, Cellular Kinetics and Exploratory Efficacy of Rapcabtagene Autoleucel in Rheumatoid Arthritis and Sjogren's Disease

 		Rheumatoid Arthritis (RA) and Sjögren's Disease (SjD) Phase1, Phase2 France
Germany
Singapore
Spain
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 NCT07048197