Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location

Open-label Extension Study of Zigakibart in Adults With IgA Nephropathy.

Kidney Diseases, Kidney Diseases, Chronic, Urological Diseases, Glomerulonephritis, Glomerular Disease, Glomerulonephritis, IGA, Glomerulopathy, Immunoglobulin Disease Phase3 United States

Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC

Prostate Cancer Phase3 Australia
China
Singapore

Study to Evaluate the Impact of Iptacopan on Top of SOC on Biopsy Changes in Kidneys of Adult Patients With IgAN

Glomerulonephritis, IGA, Immunoglobulin A Nephropathy Phase2 Malaysia
United States

A Study to Evaluate Efficacy of Remibrutinib Compared to Dupilumab at Early Timepoints in Adults With Chronic Spontaneous Urticaria Inadequately Controlled by Second Generation H1-antihistamines

Chronic Spontaneous Urticaria (CSU) Phase3 United States

A Study of JSB462 (Luxdegalutamide) Plus Lutetium (177Lu) Vipivotide Tetraxetan in Patients With Metastatic Castration Resistant Prostate Cancer (mCRPC)

Prostatic Cancer, Castration-Resistant Phase2 Israel
Singapore
United States

A Study to Assess Safety, Cellular Kinetics and Exploratory Efficacy of Rapcabtagene Autoleucel in Rheumatoid Arthritis and Sjogren's Disease

Rheumatoid Arthritis (RA) and Sjögren's Disease (SjD) Phase1, Phase2 Germany
Singapore
Spain

An Ascending Dose Study of PIT565 in Participants With Rheumatoid Arthritis

Rheumatoid Arthritis Phase1 China

Lipoprotein(a) Levels in Patients With Atherosclerotic Cardiovascular Diseases in Russia

Atherosclerotic Cardiovascular Disease Russian Federation

Inclisiran (Leqvio®) in Patients With Atherosclerotic Vascular Disease and/or Heterozygous Familial Hypercholesterolemia Treated in Spain: the INSPIRE Study

Atherosclerotic Vascular Disease, Heterozygous Familial Hypercholesterolemia Spain

Lp(a) Lowering Study of Pelacarsen (TQJ230) With Background Inclisiran in Participants With Elevated Lp(a) and Established ASCVD

Atherosclerotic Cardiovascular Disease (ASCVD) Phase3 China
Hong Kong
United States